• Explores the heterotrimeric G proteins and small G proteins of the ras/rac/rho families
• Discusses receptor structure, receptor-associated kinases, receptor desensitization, signaling mechanisms, cell-cell interactions, and more
• Details the relationship of signaling to cell cycle control
• Defines the relevance of pathways to cell control via the T cell and B cell antigen receptors and cytokine receptors
• Outlines the relationship of receptor signaling to inflammatory reactions of neutrophils, eosinophils, and macrophages

Signal Transduction in Leukocytes presents important principles and various aspects of cellular regulation in leukocytes. The book discusses receptor structure and signaling, emphasizing cytokine receptors and the T cell and B cell antigen receptors. It investigates the role of the heterotrimeric G proteins and small G proteins as transducers.

Authorities in each field cover a wide range of topics. They explore propagation of signaling cascades through second messengers and serine/threonine kinases, the initiation of signaling from the B and T cell antigen receptors by tyrosine phosphorylation and protein recruitment, and the role of signaling in cell-cell interactions and the regulation of the cell cycle. The book outlines the relationship of receptor signaling to inflammatory reactions of neutrophils, eosinophils, and macrophages.