• Serves as a comprehensive reference for academic, industrial, and governmental scientists, as well as for graduate students
• Introduces biological and environmental applications such as examination of enzyme mechanisms, hydrogen tunneling, geochemistry, and atmospheric studies
• Addresses equilibrium isotope effects, isotope effects on hydrogen bond structure and dynamics, and isotopes in polymers and biopolymers
• Examines isotope effects in chemical dynamics, hydrogen isotope effects in organic reactions, and atmospheric, geologic, and extraterrestrial studies

In the decade since the last comprehensive book on isotope effects was published, the field has expanded exponentially, and more and more researchers are using isotopes in their studies. Helping readers keep up with this trend, this book covers current principles, methods, and a broad range of applications of isotope effects in the physical, biological, and environmental sciences. The volume starts with fundamentals such as basic theory (applications of the Bigeleisen-Mayer theory), gas phase, simple condensed phase, and small molecule studies. It examines isotope effects in chemical dynamics, hydrogen isotope effects in organic reactions, and atmospheric, geologic, and extraterrestrial studies.